rstoolbox - a Python library for large-scale analysis of computational protein design data and structural bioinformatics

Bonet et al. BMC bioinformatics 2019

Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen

Sesterhenn et al. PLoS biology 2019

Rosetta FunFolDes - A general framework for the computational design of functional proteins

Bonet et al. PLoS computational biology 2018

Engineered anti-CRISPR proteins for optogenetic control of CRISPR-Cas9

Bubeck et al. Nature methods 2018

Structure-based immunogen design-leading the way to the new age of precision vaccines

Sesterhenn et al. Current opinion in structural biology 2018

Computational protein design-the next generation tool to expand synthetic biology applications

Gainza-Cirauqui and Correia Current opinion in biotechnology 2018

Global profiling of lysine reactivity and ligandability in the human proteome

Hacker et al. Nature chemistry 2017

PRN473, an inhibitor of Bruton's tyrosine kinase, inhibits neutrophil recruitment via inhibition of macrophage antigen-1 signalling

Herter et al. British journal of pharmacology 2017

Chemoproteomic profiling and discovery of protein electrophiles in human cells

Matthews et al. Nature chemistry 2017

Ligand and Target Discovery by Fragment-Based Screening in Human Cells

Parker et al. Cell 2017

Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein

Mousa et al. PNAS 2016

Proteome-wide covalent ligand discovery in native biological systems

Backus et al. Nature 2016

Protein-protein structure prediction by scoring molecular dynamics trajectories of putative poses

Sarti et al. Proteins 2016

Motif-Driven Design of Protein-Protein Interfaces

Silva et al. Methods in molecular biology 2016

Integrating gene synthesis and microfluidic protein analysis for rapid protein engineering

Blackburn et al. Nucleic acids research 2015

A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells

Niphakis et al. Cell 2015

Mapping the protein interaction landscape for fully functionalized small-molecule probes in human cells

Kambe et al. Journal of the American Chemical Society 2014

A computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein induces apoptosis in infected cells

Procko et al. Cell 2014

Proof of principle for epitope-focused vaccine design

Correia et al. Nature 2014

Reversion of somatic mutations of the respiratory syncytial virus-specific human monoclonal antibody Fab19 reveal a direct relationship between association rate and neutralizing potency

Bates et al. Journal of immunology 2013

Deciphering the molecular details for the binding of the prion protein to main ganglioside GM1 of neuronal membranes

Sanghera et al. Chemistry & biology 2011

Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold

Azoitei et al. Science 2011

High-resolution structure prediction of a circular permutation loop

Correia et al. Protein science 2011

Solution structure of a minor and transiently formed state of a T4 lysozyme mutant

Bouvignies et al. Nature 2011

Design and characterization of epitope-scaffold immunogens that present the motavizumab epitope from respiratory syncytial virus

McLellan et al. Journal of molecular biology 2011

Computational protein design using flexible backbone remodeling and resurfacing- case studies in structure-based antigen design

Correia et al. Journal of molecular biology 2010

Computational design of epitope-scaffolds allows induction of antibodies specific for a poorly immunogenic HIV vaccine epitope

Correia et al. Structure 2010

A structural model of an amyloid protofilament of transthyretin

Correia et al. Protein science 2005