rstoolbox - a Python library for large-scale analysis of computational protein design data and structural bioinformatics

Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen

Rosetta FunFolDes - A general framework for the computational design of functional proteins

Engineered anti-CRISPR proteins for optogenetic control of CRISPR-Cas9

Structure-based immunogen design-leading the way to the new age of precision vaccines

Computational protein design-the next generation tool to expand synthetic biology applications

Global profiling of lysine reactivity and ligandability in the human proteome

PRN473, an inhibitor of Bruton's tyrosine kinase, inhibits neutrophil recruitment via inhibition of macrophage antigen-1 signalling

Chemoproteomic profiling and discovery of protein electrophiles in human cells

Ligand and Target Discovery by Fragment-Based Screening in Human Cells

Structural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein

Proteome-wide covalent ligand discovery in native biological systems

Protein-protein structure prediction by scoring molecular dynamics trajectories of putative poses

Motif-Driven Design of Protein-Protein Interfaces

Integrating gene synthesis and microfluidic protein analysis for rapid protein engineering

A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells

Mapping the protein interaction landscape for fully functionalized small-molecule probes in human cells

A computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein induces apoptosis in infected cells

Proof of principle for epitope-focused vaccine design

Reversion of somatic mutations of the respiratory syncytial virus-specific human monoclonal antibody Fab19 reveal a direct relationship between association rate and neutralizing potency

Deciphering the molecular details for the binding of the prion protein to main ganglioside GM1 of neuronal membranes

Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold

High-resolution structure prediction of a circular permutation loop

Solution structure of a minor and transiently formed state of a T4 lysozyme mutant

Design and characterization of epitope-scaffold immunogens that present the motavizumab epitope from respiratory syncytial virus

Computational protein design using flexible backbone remodeling and resurfacing- case studies in structure-based antigen design

Computational design of epitope-scaffolds allows induction of antibodies specific for a poorly immunogenic HIV vaccine epitope

A structural model of an amyloid protofilament of transthyretin

A new site